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La Vida Locavore is the blog for anyone whose crazy life includes planting, growing, weeding, fertilizing, raising, picking, harvesting, processing, cooking, baking, making, serving, buying, selling, distributing, transporting, composting, organizing around, lobbying about, writing about, thinking about, talking about, playing with, and eating food!

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Change Your Lifestyle, Change Your Genes

by: Jill Richardson

Tue May 12, 2009 at 14:00:00 PM PDT


The most I ever hoped to get out of a healthy lifestyle was a change in jeans - literally, I'd like to be able to fit into my old jeans from a few years ago when I was thinner. Ok, groan, bad pun. But apparently you can actually change your GENES. THAT is some major news, huh?

Researchers tracked 30 men with low-risk prostate cancer for three months. During those three months the men underwent massive lifestyle changes and no conventional medical treatment (i.e. surgery, radiation, or chemo).

The men underwent three months of major lifestyle changes, including eating a diet rich in fruits, vegetables, whole grains, legumes and soy products, moderate exercise such as walking for half an hour a day, and an hour of daily stress management methods such as meditation.

All of the expected changes happened - lower blood pressure, etc - but the real improvement came when researchers compared the men's "before" and "after" prostate biopsies.

After the three months, the men had changes in activity in about 500 genes -- including 48 that were turned on and 453 genes that were turned off.

The activity of disease-preventing genes increased while a number of disease-promoting genes, including those involved in prostate cancer and breast cancer, shut down, according to the study published in the journal Proceedings of the National Academy of Sciences.

Amazing, huh?

Jill Richardson :: Change Your Lifestyle, Change Your Genes
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Amazing isn't the word for it. (4.00 / 7)
This is the most astonishing thing I've read in a long time. Hardly necessary to say, but I'll say it: Very Important Publication.

Thanks.


Interesting... (4.00 / 7)
Wish I could compare my genes now from those 6 or 7 years ago...

My jeans are about the same.  :)

Maybe it's just anecdotal, but I can say that since I changed my eating habits over 5 years ago, I just don't get sick anymore.  Which is a great thing since I have no health insurance these days, heh...

I went from catching like 4 or 5 colds a year 10 years ago, to maybe having one every 2 or 3 years now.  Last one I had was from a long flight.  Otherwise it probably never would have happened then, either...

I know I walk less than I used to now, though.  But to be fair, 2 years ago my commute to work involved a 1.5 mile walk from the train station every morning, and then from work back to the train every evening.  Every day, all year.  New Jersey Januaries were not fun to walk in like that.  Still, I never got sick, even walking in thundering downpours or snowstorms...

"Intelligent discontent is the mainspring of civilization." - Eugene V. Debs


Just goes to show (4.00 / 8)
eating like we evolved to eat is a good thing....

Regarding locavores as elitists - explain to me how supporting local business is elitist....

Darned Right! (4.00 / 6)
Here's an interesting story:  The "three tribes" of Mandan, Arikara, and Hidatsa lived in close proximity on the Missouri River bottoms of North Dakota for several hundred years up to about 1950. They lived well with their gardens in the rich soil and with the nuts, berries, fruits, and many kinds of meats they found in the forested landscape of the bottoms. They enjoyed a rich, supporting community life in their towns. They were healthy.

Then the Garrison Dam was built 1947-53 and the people of the tribes were forced from their homes and towns as the landscape was flooded by the dammed river.  The three tribes were forced out of the bottoms to the plateaus where the whites lived.  They were scattered, having to live in the various white towns and buy their food at the supermarkets. They lost their support communities of families, friends, and neighbors. Their health declined and they developed many diseases and mental health and behavioral problems they had not known before.

The account of this can be found in the book Coyote Warrior by Paul VanDevelder.


[ Parent ]
Wasn't there someone who did a study on (4.00 / 3)
aborigines in Australia? They were suffering from type II diabetes, heart disease, obesity, etc. and when they went back into the bush and started hunting and gathering like people used to do before the Europeans came the health issues went away?

Just goes to show, we should go back to eating whole foods. I'm sure that excersise has a lot to do with that and I don't think that everyone wants to go back to doing everything by hand, I know I sure don't want to toss my tractor, rototiller or cut more than 1/2 acre of hay with a scythe, but at least we can go back to eating whole foods that we prepare ourselves....

Regarding locavores as elitists - explain to me how supporting local business is elitist....


[ Parent ]
In the "blue zones" (I think that's what they are called) (4.00 / 1)
activity was part of daily life along with whole foods/good diet, but the activity didn't always include farming. Walking, making corn into tortillas, cutting brush are 3 that I remember.

It's really not that hard to increase your physical activity in a day. I remember when I started going out to a client in LI several times a week. I was a bit worn out and thought it was just the length of the commute until I realized I had added over a dozen sets of stairs to my day, not counting the ones in the building (3 floors no elevator). And I live in a 4th floor walk up and exercise a Dalmatian, lol!~  When I'm out and about running errands, I tend to walk fast to make sure and get my blood flowing and my body stretched out from sitting behind the computer. I'm looking forward to the weekend CSA distributions, 1 mile each way and a fair amount of lifting/carrying and all that morning sunshine :)  


[ Parent ]
Yeah... (4.00 / 1)
And I just came across that Australian study again in something I was reading like a month ago, but now I can't remember what that was.

I think it was a study from almost 30 years ago now (early 80's?), but of course it's still relevant...

"Intelligent discontent is the mainspring of civilization." - Eugene V. Debs


[ Parent ]
Just to clarify (4.00 / 5)
this isn't changing your genes.  It's changing the triggers that influence them.  It's the difference between turning light switches on and off and rewiring the house.  We've known for some time that different triggers can activate genes.

In this case, you're telling the body "you don't need to do this" and the body changes its mind.


sure (4.00 / 3)
you're not getting new genes, but you are making changes in your genes.  

"I can understand someone from Iowa promoting corn and soy, but we are not feeding the world, we are feeding animals and soft drink companies." - Jim Goodman

[ Parent ]
True, but... (4.00 / 1)
Just wanted to chime in here and mention that while this finding is cool and important, it is nothing unique. Everything we eat affects gene expression all over our bodies. Not just food, but also stress, experience, our environment, exercise, etc. This is how biology works.

My day job is studying molecular biology/genetics, in case you were wondering  :)


[ Parent ]
Dr. Judith Rich, who posts on (4.00 / 3)
Huffington Post, was just diagnosed with breast cancer.  She has a post about her journey here -- and includes a very interesting video at the end that underscores the findings you write about here, Jill.

Thank you for fixing that! (4.00 / 3)
I should have checked it.

[ Parent ]
Good video. (4.00 / 3)
I like the phrase "false hopelessness."

7 minutes.


[ Parent ]
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